Synthesis of 4-Amino-4,5-dihydro-1H-1,2,4-triazole-5-ones and their Isatin-3-imine Derivatives

doi:10.3390/10020376

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Molecules 2005, 10(2), 376-382; doi:10.3390/10020376

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Synthesis of 4-Amino-4,5-dihydro-1H-1,2,4-triazole-5-ones and their Isatin-3-imine Derivatives

Bahittin Kahveci

Department of Chemistry, Rize Faculty of Arts and Science, Karadeniz Technical University, 53100,Rize, Turkey

Received: 12 July 2004 / Accepted: 1 September 2004 / Published: 28 February 2005

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Abstract: Iminoester hydrochlorides 1 have been synthesized. These compounds werethen converted into ester ethoxycarbonyl hydrazones 2, from which in turn a new seriesof substituted 4-amino-4,5-dihydro-1H-1,2,4-triazole-5-ones, 3, was then prepared.Finally a set of isatin imine derivatives 4 was obtained from the reaction of compounds 3with isatin. The structures of all the new synthesized compounds were confirmed byelemental analyses, IR, ¹H-NMR and ¹³C-NMR spectra.

Keywords: Iminoesters; ethoxycarbonyl hydrazones; 4-amino-1; 2; 4-triazole-5-ones; isatin

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MDPI and ACS Style

Kahveci, B. Synthesis of 4-Amino-4,5-dihydro-1H-1,2,4-triazole-5-ones and their Isatin-3-imine Derivatives. Molecules 2005, 10, 376-382.

AMA Style

Kahveci B. Synthesis of 4-Amino-4,5-dihydro-1H-1,2,4-triazole-5-ones and their Isatin-3-imine Derivatives. Molecules. 2005; 10(2):376-382.

Chicago/Turabian Style

Kahveci, Bahittin. 2005. "Synthesis of 4-Amino-4,5-dihydro-1H-1,2,4-triazole-5-ones and their Isatin-3-imine Derivatives." Molecules 10, no. 2: 376-382.

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