Next Article in Journal
Previous Article in Journal
Molecules 2005, 10(11), 1387-1398; doi:10.3390/10111387
Article

N,N’-Substituted 1,2,5 Thiadiazolidine 1,1-Dioxides: Synthesis, Selected Chemical and Spectral Proprieties and Antimicrobial Evaluation †

, ,  and *
Received: 28 June 2005; in revised form: 5 September 2005 / Accepted: 10 September 2005 / Published: 30 November 2005
Download PDF [96 KB, uploaded 18 June 2014]
Abstract: The sulfamide functional group is increasingly relevant in both medicinal and bioorganic chemistry. We report here practical access to a series of N2,N5-substituted five-membered cyclosulfamides. The five-membered heterocyclic motif was prepared starting from proteogenic amino acids and chlorosulfonyl isocyanate via the Mitsunobu reaction. Selected chemical and spectral proprieties and the antimicrobial evaluation of these compounds are detailed.
Keywords: Amino acids; cyclic sulfamides; cyclization; Mitsunobu reaction; propionylation; constrained peptides. Amino acids; cyclic sulfamides; cyclization; Mitsunobu reaction; propionylation; constrained peptides.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Bendjeddou, A.; Djeribi, R.; Regainia, Z.; Aouf, N. N,N’-Substituted 1,2,5 Thiadiazolidine 1,1-Dioxides: Synthesis, Selected Chemical and Spectral Proprieties and Antimicrobial Evaluation †. Molecules 2005, 10, 1387-1398.

AMA Style

Bendjeddou A, Djeribi R, Regainia Z, Aouf N. N,N’-Substituted 1,2,5 Thiadiazolidine 1,1-Dioxides: Synthesis, Selected Chemical and Spectral Proprieties and Antimicrobial Evaluation †. Molecules. 2005; 10(11):1387-1398.

Chicago/Turabian Style

Bendjeddou, A.; Djeribi, R.; Regainia, Z.; Aouf, N. 2005. "N,N’-Substituted 1,2,5 Thiadiazolidine 1,1-Dioxides: Synthesis, Selected Chemical and Spectral Proprieties and Antimicrobial Evaluation †." Molecules 10, no. 11: 1387-1398.


Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert