Next Article in Journal / Special Issue
Syntheses, Characterization and Study of the Use of Cobalt (II) Schiff–Base Complexes as Catalysts for the Oxidation of Styrene by Molecular Oxygen
Previous Article in Journal / Special Issue
An Electron Transfer Approach to the Preparation of Highly Functionalized Anthraquinones
Article Menu

Export Article

Open AccessArticle
Molecules 2005, 10(1), 295-301; doi:10.3390/10010295

Synthesis of Analogs of Amathamide A and Their Preliminary Antimicrobial Activity

1
Centro de Graduados e Investigación, Instituto Tecnológico de Tijuana, México
2
Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, México
3
Instituto de Ciencia de Materiales de Barcelona (CSIC), Spain
*
Author to whom correspondence should be addressed.
Received: 20 August 2004 / Revised: 6 January 2005 / Accepted: 7 January 2005 / Published: 31 January 2005
(This article belongs to the Special Issue Hypervalent Iodine)
View Full-Text   |   Download PDF [171 KB, uploaded 18 June 2014]   |  

Abstract

Syntheses of three non-brominated analogs of amathamide A (1), a natural alkaloid isolated from the Tasmanian marine bryozoan Amathia wilsoni, are described. Antimicrobial activity against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomona aeruginosa, and Candida albicans was tested. Test results for amathamide A (1) showed a weak activity against C. albicans and E. coli. The three non-natural analogs 2-4 proved to be inactive compounds.
Keywords: Organic synthesis; Amathamide A; Antimicrobial activity. Organic synthesis; Amathamide A; Antimicrobial activity.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Ramírez-Osuna, M.; Chávez, D.; Hernández, L.; Molins, E.; Somanathan, R.; Aguirre, G. Synthesis of Analogs of Amathamide A and Their Preliminary Antimicrobial Activity. Molecules 2005, 10, 295-301.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top