Molecules 2005, 10(1), 295-301; doi:10.3390/10010295
Article

Synthesis of Analogs of Amathamide A and Their Preliminary Antimicrobial Activity

1, 1, 2, 3, 1 and 1,* email
Received: 20 August 2004; in revised form: 6 January 2005 / Accepted: 7 January 2005 / Published: 31 January 2005
(This article belongs to the Special Issue Hypervalent Iodine)
Download PDF [171 KB, uploaded 18 June 2014]
Abstract: Syntheses of three non-brominated analogs of amathamide A (1), a natural alkaloid isolated from the Tasmanian marine bryozoan Amathia wilsoni, are described. Antimicrobial activity against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomona aeruginosa, and Candida albicans was tested. Test results for amathamide A (1) showed a weak activity against C. albicans and E. coli. The three non-natural analogs 2-4 proved to be inactive compounds.
Keywords: Organic synthesis; Amathamide A; Antimicrobial activity.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Ramírez-Osuna, M.; Chávez, D.; Hernández, L.; Molins, E.; Somanathan, R.; Aguirre, G. Synthesis of Analogs of Amathamide A and Their Preliminary Antimicrobial Activity. Molecules 2005, 10, 295-301.

AMA Style

Ramírez-Osuna M, Chávez D, Hernández L, Molins E, Somanathan R, Aguirre G. Synthesis of Analogs of Amathamide A and Their Preliminary Antimicrobial Activity. Molecules. 2005; 10(1):295-301.

Chicago/Turabian Style

Ramírez-Osuna, M.; Chávez, D.; Hernández, L.; Molins, E.; Somanathan, R.; Aguirre, G. 2005. "Synthesis of Analogs of Amathamide A and Their Preliminary Antimicrobial Activity." Molecules 10, no. 1: 295-301.


Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert