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Molecules 2005, 10(1), 279-288; doi:10.3390/10010279
Article

Chemical and Photochemical Synthesis of Substituted Dihydro-thieno[2',3':4,5]thieno[2,3-c]quinolin-6-ones and Tetrahydro-dithieno[2,3-b:2',3'-d]thieno[2'',3''c:2'',3''c’]diquinolin-6,14-dione

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Received: 28 September 2004; in revised form: 2 November 2004 / Accepted: 30 December 2004 / Published: 31 January 2005
(This article belongs to the Special Issue Hypervalent Iodine)
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Abstract: Some new substituted dihydrothieno[2',3':4,5]thieno[2,3-c]quinolin-6-ones 9- 12 and tetrahydrodithieno[2,3-b: 2',3'-d]thieno[2'',3''-c:2'',3''-c’]diquinolin-6,14-dione (17) were prepared from the corresponding new anilides 5-8 and from the corresponding dianilide 15, respectively, by a multistep combination of chemical and photochemical reactions. All the prepared compounds are of particular interest because they might serve as DNA intercalators in anticancer therapy.
Keywords: Substituted dihydrothieno[2'; 3':4; 5]thieno[2; 3-c]quinolin-6-ones; Tetra- hydrodithieno[2; 3-b:2'; 3'-d]thieno[2''; 3''c:2''; 3''c’]diquinolin-6; 14-dione; Synthesis; Photo- chemical synthesis; DNA Intercalators; Anticancer therapy. Substituted dihydrothieno[2'; 3':4; 5]thieno[2; 3-c]quinolin-6-ones; Tetra- hydrodithieno[2; 3-b:2'; 3'-d]thieno[2''; 3''c:2''; 3''c’]diquinolin-6; 14-dione; Synthesis; Photo- chemical synthesis; DNA Intercalators; Anticancer therapy.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Šafarik, J.B.; Koružnjak, J.D.; Karminski-Zamola, G. Chemical and Photochemical Synthesis of Substituted Dihydro-thieno[2',3':4,5]thieno[2,3-c]quinolin-6-ones and Tetrahydro-dithieno[2,3-b:2',3'-d]thieno[2'',3''c:2'',3''c’]diquinolin-6,14-dione. Molecules 2005, 10, 279-288.

AMA Style

Šafarik JB, Koružnjak JD, Karminski-Zamola G. Chemical and Photochemical Synthesis of Substituted Dihydro-thieno[2',3':4,5]thieno[2,3-c]quinolin-6-ones and Tetrahydro-dithieno[2,3-b:2',3'-d]thieno[2'',3''c:2'',3''c’]diquinolin-6,14-dione. Molecules. 2005; 10(1):279-288.

Chicago/Turabian Style

Šafarik, Jelena B.; Koružnjak, Jasna D.; Karminski-Zamola, Grace. 2005. "Chemical and Photochemical Synthesis of Substituted Dihydro-thieno[2',3':4,5]thieno[2,3-c]quinolin-6-ones and Tetrahydro-dithieno[2,3-b:2',3'-d]thieno[2'',3''c:2'',3''c’]diquinolin-6,14-dione." Molecules 10, no. 1: 279-288.


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