Molecules 2005, 10(1), 279-288; doi:10.3390/10010279
Article

Chemical and Photochemical Synthesis of Substituted Dihydro-thieno[2',3':4,5]thieno[2,3-c]quinolin-6-ones and Tetrahydro-dithieno[2,3-b:2',3'-d]thieno[2'',3''c:2'',3''c’]diquinolin-6,14-dione

Jelena Blažević Šafarik, Jasna Dogan Koružnjak and Grace Karminski-Zamolaemail
Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 20, 10000 Zagreb, Croatia
* Author to whom correspondence should be addressed.
Received: 28 September 2004; in revised form: 2 November 2004 / Accepted: 30 December 2004 / Published: 31 January 2005
(This article belongs to the Special Issue Hypervalent Iodine)
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Abstract: Some new substituted dihydrothieno[2',3':4,5]thieno[2,3-c]quinolin-6-ones 9- 12 and tetrahydrodithieno[2,3-b: 2',3'-d]thieno[2'',3''-c:2'',3''-c’]diquinolin-6,14-dione (17) were prepared from the corresponding new anilides 5-8 and from the corresponding dianilide 15, respectively, by a multistep combination of chemical and photochemical reactions. All the prepared compounds are of particular interest because they might serve as DNA intercalators in anticancer therapy.
Keywords: Substituted dihydrothieno[2'; 3':4; 5]thieno[2; 3-c]quinolin-6-ones; Tetra- hydrodithieno[2; 3-b:2'; 3'-d]thieno[2''; 3''c:2''; 3''c’]diquinolin-6; 14-dione; Synthesis; Photo- chemical synthesis; DNA Intercalators; Anticancer therapy.

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MDPI and ACS Style

Šafarik, J.B.; Koružnjak, J.D.; Karminski-Zamola, G. Chemical and Photochemical Synthesis of Substituted Dihydro-thieno[2',3':4,5]thieno[2,3-c]quinolin-6-ones and Tetrahydro-dithieno[2,3-b:2',3'-d]thieno[2'',3''c:2'',3''c’]diquinolin-6,14-dione. Molecules 2005, 10, 279-288.

AMA Style

Šafarik JB, Koružnjak JD, Karminski-Zamola G. Chemical and Photochemical Synthesis of Substituted Dihydro-thieno[2',3':4,5]thieno[2,3-c]quinolin-6-ones and Tetrahydro-dithieno[2,3-b:2',3'-d]thieno[2'',3''c:2'',3''c’]diquinolin-6,14-dione. Molecules. 2005; 10(1):279-288.

Chicago/Turabian Style

Šafarik, Jelena B.; Koružnjak, Jasna D.; Karminski-Zamola, Grace. 2005. "Chemical and Photochemical Synthesis of Substituted Dihydro-thieno[2',3':4,5]thieno[2,3-c]quinolin-6-ones and Tetrahydro-dithieno[2,3-b:2',3'-d]thieno[2'',3''c:2'',3''c’]diquinolin-6,14-dione." Molecules 10, no. 1: 279-288.

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