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Entropy 2017, 19(6), 282;

Correntropy-Based Pulse Rate Variability Analysis in Children with Sleep Disordered Breathing

Biomedical Signals and Systems Group, Faculty of Electrical Engineering, Mathematics & Computer Science, University of Twente, 7500 AE Enschede, The Netherlands
Department of Electrical & Computer Engineering, The University of British Columbia, Vancouver, BC V6T 1Z4, Canada
Department of Anesthesiology, Pharmacology & Therapeutics, The University of British Columbia, Vancouver, BC V6T 1Z3, Canada
Author to whom correspondence should be addressed.
Received: 6 May 2017 / Revised: 7 June 2017 / Accepted: 9 June 2017 / Published: 16 June 2017
(This article belongs to the Special Issue Entropy and Sleep Disorders)
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Pulse rate variability (PRV), an alternative measure of heart rate variability (HRV), is altered during obstructive sleep apnea. Correntropy spectral density (CSD) is a novel spectral analysis that includes nonlinear information. We recruited 160 children and recorded SpO2 and photoplethysmography (PPG), alongside standard polysomnography. PPG signals were divided into 1-min epochs and apnea/hypoapnea (A/H) epochs labeled. CSD was applied to the pulse-to-pulse interval time series (PPIs) and five features extracted: the total spectral power (TP: 0.01–0.6 Hz), the power in the very low frequency band (VLF: 0.01–0.04 Hz), the normalized power in the low and high frequency bands (LFn: 0.04–0.15 Hz, HFn: 0.15–0.6 Hz), and the LF/HF ratio. Nonlinearity was assessed with the surrogate data technique. Multivariate logistic regression models were developed for CSD and power spectral density (PSD) analysis to detect epochs with A/H events. The CSD-based features and model identified epochs with and without A/H events more accurately relative to PSD-based analysis (area under the curve (AUC) 0.72 vs. 0.67) due to the nonlinearity of the data. In conclusion, CSD-based PRV analysis provided enhanced performance in detecting A/H epochs, however, a combination with overnight SpO2 analysis is suggested for optimal results. View Full-Text
Keywords: pulse rate variability; correntropy; smartphone-based pulse oximetry pulse rate variability; correntropy; smartphone-based pulse oximetry

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Garde, A.; Dehkordi, P.; Ansermino, J.M.; Dumont, G.A. Correntropy-Based Pulse Rate Variability Analysis in Children with Sleep Disordered Breathing. Entropy 2017, 19, 282.

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