Next Article in Journal
A Risk-Free Protection Index Model for Portfolio Selection with Entropy Constraint under an Uncertainty Framework
Next Article in Special Issue
Quantitative EEG Markers of Entropy and Auto Mutual Information in Relation to MMSE Scores of Probable Alzheimer’s Disease Patients
Previous Article in Journal
Admitting Spontaneous Violations of the Second Law in Continuum Thermomechanics
Previous Article in Special Issue
Classification of Normal and Pre-Ictal EEG Signals Using Permutation Entropies and a Generalized Linear Model as a Classifier
Article Menu
Issue 2 (February) cover image

Export Article

Open AccessArticle
Entropy 2017, 19(2), 81; doi:10.3390/e19020081

Towards Operational Definition of Postictal Stage: Spectral Entropy as a Marker of Seizure Ending

1
Unidad de Neurocirugía de la Epilepsia, Instituto de Investigación Sanitaria Hospital de la Princesa, 28006 Madrid, Spain
2
Neurofisiología Clínica, Hospital Universitario de la Princesa, 28006 Madrid, Spain
3
Neurocirugía, Hospital Universitario de la Princesa, 28006 Madrid, Spain
4
The National Scientific and Technical Research Council (CONICET), Av. Rivadavia 1917, C1033AAJ, Buenos Aires, Argentina
*
Author to whom correspondence should be addressed.
Academic Editors: Kevin H. Knuth and Osvaldo Anibal Rosso
Received: 29 November 2016 / Revised: 15 February 2017 / Accepted: 16 February 2017 / Published: 21 February 2017
(This article belongs to the Special Issue Entropy and Electroencephalography II)
View Full-Text   |   Download PDF [2703 KB, uploaded 21 February 2017]   |  

Abstract

The postictal period is characterized by several neurological alterations, but its exact limits are clinically or even electroencephalographically hard to determine in most cases. We aim to provide quantitative functions or conditions with a clearly distinguishable behavior during the ictal-postictal transition. Spectral methods were used to analyze foramen ovale electrodes (FOE) recordings during the ictal/postictal transition in 31 seizures of 15 patients with strictly unilateral drug resistant temporal lobe epilepsy. In particular, density of links, spectral entropy, and relative spectral power were analyzed. Partial simple seizures are accompanied by an ipsilateral increase in the relative Delta power and a decrease in synchronization in a 66% and 91% of the cases, respectively, after seizures offset. Complex partial seizures showed a decrease in the spectral entropy in 94% of cases, both ipsilateral and contralateral sides (100% and 73%, respectively) mainly due to an increase of relative Delta activity. Seizure offset is defined as the moment at which the “seizure termination mechanisms” actually end, which is quantified in the spectral entropy value. We propose as a definition for the postictal start the time when the ipsilateral SE reaches the first global minimum. View Full-Text
Keywords: temporal lobe epilepsy; synchronization; graph theory; limbic network; foramen ovale electrodes; postictal; entropy temporal lobe epilepsy; synchronization; graph theory; limbic network; foramen ovale electrodes; postictal; entropy
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Sanz-García, A.; Vega-Zelaya, L.; Pastor, J.; Sola, R.G.; Ortega, G.J. Towards Operational Definition of Postictal Stage: Spectral Entropy as a Marker of Seizure Ending. Entropy 2017, 19, 81.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Entropy EISSN 1099-4300 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top