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Medicina 2018, 54(4), 50; https://doi.org/10.3390/medicina54040050

Human Papilloma Virus (HPV) and Fertilization: A Mini Review

1
School of Health Sciences, Faculty of Medicine, Department of Obstetrics and Gynaecology, University of Thessaly, Biopolis, T.K., 42200 Larissa, Greece
2
School of Health Sciences, Faculty of Medicine, Department of Morphology, University of Thessaly, Biopolis, T.K., 42200 Larissa, Greece
3
School of Health Sciences, Faculty of Medicine, Department of Biology, University of Thessaly, Biopolis, T.K., 42200 Larissa, Greece
*
Author to whom correspondence should be addressed.
Received: 29 May 2018 / Revised: 19 July 2018 / Accepted: 24 July 2018 / Published: 27 July 2018
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Abstract

Human papilloma virus (HPV) is one of the most prevalent viral sexually transmitted diseases. The ability of HPV to induce malignancy in the anogenital tract and stomato-pharyngeal cavity is well documented. Moreover, HPV infection may also affect reproductive health and fertility. Although, the impact of HPV on female fertility has not been thoroughly studied it has been found also to have an impact on semen parameters. Relative information can be obtained from studies investigating the relationship between HPV and pregnancy success. Furthermore, there is an ongoing debate whether HPV alters the efficacy of assisted reproductive technologies. An association between HPV and assisted reproductive technologies (ART) programs has been reported. Nevertheless, due to conflicting data and the small number of existing studies further research is required. It remains to be clarified whether HPV detection and genotyping could be included in the diagnostic procedures in couples undergoing in vitro fertilization (IVF)/intrauterine insemination (IUI) treatments. Vaccination of both genders against HPV can reduce the prevalence of HPV infection and eliminate its implications on human fertility. The aim of the present mini-review is to reiterate the association between HPV and human fertility through a systematic literature review. View Full-Text
Keywords: HPV; fertility; semen; cryopreservation; assisted reproductive technology; IVF HPV; fertility; semen; cryopreservation; assisted reproductive technology; IVF
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
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Zacharis, K.; Messini, C.I.; Anifandis, G.; Koukoulis, G.; Satra, M.; Daponte, A. Human Papilloma Virus (HPV) and Fertilization: A Mini Review. Medicina 2018, 54, 50.

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